Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108441 | 0.88 | HPGD (0.50) | KMT2AMEN1HPGDCYP1A2CYP2D6 | |
| SCHEMBL7106735 | 0.84 | HPGD (0.45) | KMT2AMEN1HPGDALDH1A1HRH3 | |
| SCHEMBL19455128 | 0.81 | HPGD (0.52) | HPGDCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20869253 | 0.81 | KDM4E (0.59) | HPGDCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL7106738 | 0.80 | HPGD (0.44) | KMT2AMEN1HPGDCYP1A2CYP2D6 | |
| SCHEMBL8276090 | 0.80 | NFE2L2 (0.62) | KMT2AMEN1HPGDALDH1A1HRH3 | |
| SCHEMBL13907677 | 0.79 | KMT2A (0.54) | KMT2AMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4964015 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1TSHRHRH3 | |
| SCHEMBL11733801 | 0.78 | HRH3 (0.52) | HPGDCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11519998 | 0.78 | NFE2L2 (0.63) | HPGDCYP1A2CYP2D6CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113005-B1 | Sulfonium salt compounds | WAKO PURE CHEM IND LTD (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1238969-A2 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-1113005-A1 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2001-07-04 | — | — | EP | disclosed |