Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258862 | 0.79 | ALOX5 (0.53) | NPC1RAB9AALOX5KMT2APOLB | |
| SCHEMBL28089140 | 0.77 | HCAR2 (0.51) | NPC1RAB9AALOX5KMT2APOLB | |
| SCHEMBL30322580 | 0.76 | ALOX5 (0.42) | NPC1RAB9AALOX5KMT2APOLB | |
| SCHEMBL27884913 | 0.75 | KMT2A (0.42) | NPC1RAB9AALOX5KMT2APOLB | |
| SCHEMBL11047695 | 0.75 | ALOX5 (0.41) | ALOX5KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL14073828 | 0.75 | ALOX5 (0.41) | NPC1RAB9AALOX5KMT2APOLB | |
| SCHEMBL28089141 | 0.72 | HCAR2 (0.62) | ALOX5KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL28453165 | 0.72 | ALDH1A1 (0.41) | ALOX5KMT2APOLBMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL7020677 | 0.71 | HCAR2 (0.60) | ALOX5KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL1153462 | 0.71 | ALOX5 (0.41) | ALOX5KMT2APOLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242724-A1 | Acid decomposable compound | SAITO YUTAKA (JP) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242724-A1 | Acid decomposable compound | DERA, ALDOA, DHPS | NPC1 2846/4885RAB9A 1931/4885ALOX5 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.