Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP12 | P39900 | 4/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937175 | 0.88 | HTR1A (0.52) | IDO1MEN1POLBKMT2AMMP2 | |
| SCHEMBL4808474 | 0.85 | MEN1 (0.66) | MEN1POLBKMT2AMMP2MMP9 | |
| SCHEMBL7116833 | 0.84 | IDO1 (0.49) | IDO1MEN1POLBKMT2AMMP2 | |
| SCHEMBL8230220 | 0.81 | MEN1 (0.61) | MEN1POLBKMT2AMMP2MMP9 | |
| SCHEMBL4446703 | 0.81 | SLC6A4 (0.56) | MEN1POLBKMT2AMMP2MMP9 | |
| SCHEMBL14098013 | 0.80 | IDO1 (0.43) | IDO1MEN1POLBKMT2AMMP2 | |
| SCHEMBL7108668 | 0.80 | KMT2A (0.49) | IDO1MEN1POLBKMT2AMMP2 | |
| SCHEMBL14098030 | 0.80 | IDO1 (0.43) | IDO1MMP2MMP9MMP12SLC6A4 | |
| SCHEMBL14098342 | 0.78 | HTR1A (0.52) | MEN1POLBKMT2AMMP2MMP9 | |
| SCHEMBL14138591 | 0.78 | IDO1 (0.41) | IDO1MEN1POLBKMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | YAMASHITA SHINYA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6495592-B1 | DIBENZ(B,F)OXEPIN DERIVATIVES; ANTIASTHMATICS | NIPPON SUISAN KAISHA, LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| US-6180659-B1 | USING A DIBENZO(B,F)-(OXEPIN OR THIEPIN) COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0885610-A1 | TRACHEAL SMOOTH MUSCLE RELAXANT | NIPPON SUISAN KAISHA, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | MYLK, MUSK, CPT1B | IDO1 2322/4885MEN1 4726/4885POLB 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.