Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 9/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170268 | 0.94 | PTGS2 (0.50) | PTGS2RPS6KA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7114909 | 0.92 | PTGS2 (0.49) | PTGS2RPS6KA3PTGS1PIK3CDPIK3CA | |
| SCHEMBL7114859 | 0.89 | PTGS2 (0.52) | PTGS2RPS6KA3PTGS1SLC22A12CYP17A1 | |
| SCHEMBL7115512 | 0.89 | PTGS2 (0.52) | PTGS2RPS6KA3PTGS1CYP17A1 | |
| SCHEMBL7109862 | 0.89 | PTGS2 (0.46) | PTGS2RPS6KA3PTGS1PIK3CDPIK3CA | |
| SCHEMBL7538657 | 0.89 | PTGS2 (0.46) | PTGS2RPS6KA3PTGS1PIK3CDPIK3CA | |
| SCHEMBL7546134 | 0.88 | RPS6KA3 (0.61) | PTGS2RPS6KA3PTGS1PIK3CDPIK3CA | |
| SCHEMBL7111676 | 0.88 | PTGS2 (0.49) | PTGS2RPS6KA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL6729069 | 0.88 | PTGS2 (0.50) | PTGS2RPS6KA3PTGS1SLC22A12CYP17A1 | |
| SCHEMBL6735040 | 0.87 | RPS6KA3 (0.50) | PTGS2RPS6KA3PTGS1SLC22A12CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296971-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2003-04-02 | — | — | EP | disclosed |
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2002-12-05 | — | — | US | disclosed |
| WO-2001081332-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, FPR1, PTGES2 | PTGS2 5/4885RPS6KA3 1119/4885PTGS1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.