SCHEMBL7108780

SCHEMBL7108780

C[Si](C)(C)C(CS)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.39
GAA P10253 1/20 0.37
TAAR1 Q96RJ0 4/20 0.37
HTR2A P28223 4/20 0.37
HRH1 P35367 3/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
CPA3 P15088 1/20 0.35
FOLH1 Q04609 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9395013 0.77 TAAR1 (0.52) TAAR1HTR2AHRH1
SCHEMBL3108768 0.77 TAAR1 (0.37) TAAR1HTR2AHRH1LMNATDP1
SCHEMBL20994305 0.77 KMT2A (0.38)
SCHEMBL29000457 0.76 AOC3 (0.43) TAAR1HTR2AHRH1LMNA
SCHEMBL31465223 0.76 SLC6A2 (0.48) ANPEPTAAR1HTR2AHRH1
SCHEMBL29233483 0.74 HRH1 (0.36) TAAR1HTR2AHRH1LMNATDP1
SCHEMBL8071269 0.72 CYP2C19 (0.36) TAAR1HTR2AHRH1LMNATDP1
SCHEMBL28957363 0.72 CYP2C19 (0.47) TAAR1HTR2AHRH1LMNA
SCHEMBL9722923 0.71 CSNK1E (0.42) HTR2A
SCHEMBL18397578 0.70 CYP2C19 (0.33) TAAR1HTR2AHRH1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1345877-A1 AMINE MODIFIED CATALYSTS FOR BISPHENOL PRODUCTION GENERAL ELECTRIC COMPANY (US) 2003-09-24 EP claimed
WO-2002050000-A1 AMINE MODIFIED CATALYSTS FOR BISPHENOL PRODUCTION GENERAL ELECTRIC COMPANY (US) 2002-06-27 WO claimed