Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939784 | 0.79 | PTGS1 (0.53) | CYP2D6 | |
| SCHEMBL7108780 | 0.77 | ANPEP (0.39) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL9395013 | 0.77 | TAAR1 (0.52) | TAAR1HTR2AHRH1SLC6A3CYP2D6 | |
| SCHEMBL8071269 | 0.77 | CYP2C19 (0.36) | TAAR1HTR2AHRH1LMNAGRM2 | |
| SCHEMBL31465223 | 0.76 | SLC6A2 (0.48) | TAAR1HTR2AHRH1SLC6A3CYP2D6 | |
| SCHEMBL29000457 | 0.76 | AOC3 (0.43) | TAAR1HTR2AHRH1LMNA | |
| SCHEMBL29233483 | 0.74 | HRH1 (0.36) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL3103406 | 0.72 | ALDH1A1 (0.33) | TAAR1HTR2AHRH1LMNAGRM2 | |
| SCHEMBL1695057 | 0.72 | MTNR1A (0.42) | LMNASLC6A3CYP2D6 | |
| SCHEMBL28957363 | 0.72 | CYP2C19 (0.47) | TAAR1HTR2AHRH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786476-B | compounds as opioid receptor modulators | 詹森药业有限公司 | 2017-01-18 | — | — | CN | disclosed |
| US-7759494-B2 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxy-carbonyl]-5-oxazolidine carboxylic acids | DABUR INDIA LIMITED (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20080064887-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids | DABUR INDIA LIMITED (IN) | 2008-03-13 | — | — | US | disclosed |
| US-20030229135-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbonyl]-5-oxazolidine carboxylic acids | DABUR PHARMA LIMITED (IN) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229135-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbonyl]-5-oxazolidine carboxylic acids | TBCA, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TUBAL3 | TAAR1 2289/4885HTR2A 3625/4885HRH1 2769/4885 |
| US-20080064887-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids | TBCA, TUBAL3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TAAR1 1870/4885HTR2A 3117/4885HRH1 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.