SCHEMBL8071269

SCHEMBL8071269

C[Si](C)(C)C(CS(=O)(=O)CC(c1ccccc1)[Si](C)(C)C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.36
PSIP1 O75475 1/20 0.34
SRC P12931 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
POLB P06746 2/20 0.33
HSD11B1 P28845 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GRIA4 P48058 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108768 0.77 TAAR1 (0.37) SRCLMNATAAR1TDP1HTR2A
SCHEMBL9395013 0.72 TAAR1 (0.52) CYP2C19TAAR1HTR2AHRH1
SCHEMBL7108780 0.72 ANPEP (0.39) LMNATAAR1TDP1HTR2AHRH1
SCHEMBL29000457 0.71 AOC3 (0.43) LMNAALDH1A1TAAR1POLBMAPT
SCHEMBL31465223 0.71 SLC6A2 (0.48) TAAR1HTR2AHRH1
SCHEMBL29233483 0.69 HRH1 (0.36) CYP2C19LMNATAAR1TDP1HTR2A
SCHEMBL17287844 0.68 GBA1 (0.52)
SCHEMBL12922884 0.68 LMNA (0.43) CYP2C19PSIP1SRCLMNATAAR1
SCHEMBL4133196 0.68 CYP2C19 (0.39) CYP2C19SRCALDH1A1TAAR1HSD11B1
SCHEMBL3103406 0.68 ALDH1A1 (0.33) CYP2C19LMNAALDH1A1TAAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-5919552-A Coated substrates and methods XEROX CORPORATION (US) 1999-07-06 US claimed
US-5919552-A Coated substrates and methods XEROX CORPORATION (US) 1999-07-06 US disclosed