Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.60 |
| ▸ | CCR1 | P32246 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | CCR8 | P51685 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548441 | 0.86 | CCR1 (0.66) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| Dipyridyl SCHEMBL28995270 | 0.82 | KDM4E (0.64) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| Terpyridine SCHEMBL7112915 | 0.80 | KDM4E (0.95) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| Terpyridine SCHEMBL1616654 | 0.80 | KDM4E (0.95) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| SCHEMBL7549260 | 0.79 | CCR1 (0.59) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| SCHEMBL7549135 | 0.78 | LMNA (0.41) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| Terpyridine SCHEMBL2406854 | 0.78 | KDM4E (0.82) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| SCHEMBL6246649 | 0.78 | KMT2A (0.60) | KDM4EL3MBTL1SMN1; SMN2HTTCYP1A2 | |
| Terpyridine SCHEMBL30610403 | 0.78 | KDM4E (0.90) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 | |
| Terpyridine SCHEMBL57442 | 0.78 | KDM4E (1.00) | KDM4EL3MBTL1SMN1; SMN2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885233-B1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION (GB) | 2002-06-19 | — | — | EP | claimed |
| EP-1144423-B1 | BIS-TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION (GB) | 2003-10-22 | — | — | EP | disclosed |
| EP-0885233-B1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION (GB) | 2002-06-19 | — | — | EP | disclosed |
| US-20020013306-A1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION LIMITED (GB) | 2002-01-31 | — | — | US | disclosed |
| EP-1164138-A1 | Terpyridine-platinum (II) complexes | ISIS INNOVATION LIMITED (GB) | 2001-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013306-A1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | TOP2A, TOP1, TOP2B | KDM4E 4584/4885L3MBTL1 2025/4885SMN1; SMN2 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.