⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397862 | 0.79 | — | — | |
| SCHEMBL9191039 | 0.79 | TDP1 (0.35) | — | |
| SCHEMBL8743496 | 0.78 | AR (0.31) | — | |
| SCHEMBL8741753 | 0.75 | — | — | |
| SCHEMBL28835487 | 0.71 | TDP1 (0.33) | — | |
| SCHEMBL9191053 | 0.71 | — | — | |
| SCHEMBL4833943 | 0.71 | POLB (0.35) | — | |
| SCHEMBL28880448 | 0.70 | LMNA (0.36) | — | |
| SCHEMBL4830946 | 0.70 | LMNA (0.40) | — | |
| SCHEMBL9614722 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353899-A1 | A PROCESS FOR THE PREPARATION OF IOPAMIDOL AND THE NEW INTERMEDIATES THEREIN | Bracco Imaging S.p.A. (IT) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002044132-A1 | A PROCESS FOR THE PREPARATION OF IOPAMIDOL AND THE NEW INTERMEDIATES THEREIN | BRACCO IMAGING S.P.A. (IT) | 2002-06-06 | — | — | WO | disclosed |
| EP-0516050-A2 | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures | BRACCO INTERNATIONAL B.V. (NL) | 1992-12-02 | — | — | EP | disclosed |