Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 11/20 | 0.51 |
| ▸ | LOX | P28300 | 3/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595539 | 0.85 | GABRG2 (0.43) | LOXL2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL27741183 | 0.85 | GABRG2 (0.42) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL4441732 | 0.83 | LOXL2 (0.55) | LOXL2LOXLOXL3SMYD3 | |
| SCHEMBL3882564 | 0.80 | GABRG2 (0.45) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL190479 | 0.79 | SMN1; SMN2 (0.41) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL15561762 | 0.78 | SLC7A5 (0.46) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL13105640 | 0.78 | GABRG2 (0.46) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL3700486 | 0.78 | GABRG2 (0.46) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL163615 | 0.78 | GABRG2 (0.46) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL29563011 | 0.78 | GABRG2 (0.46) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491348-C | Thrombosis resisting preparation | ASTRAZENECA AB (SE) | 2009-05-27 | — | — | CN | disclosed |
| CN-1515550-A | Thrombosis resisting preparation | — | 2004-07-28 | — | — | CN | disclosed |
| CN-1134264-C | antithrombotic agent | — | 2004-01-14 | — | — | CN | disclosed |
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | disclosed |
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | disclosed |
| US-5914319-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| US-5726159-A | PEPTIDE THROMBIN INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5710130-A | HETEROCYCLIC SYNTHETIC PEPTIDES | ELI LILLY AND COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5707966-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5705487-A | PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| CN-1147205-A | antithrombotic agent | LILLY CO ELI (US) | 1997-04-09 | — | — | CN | disclosed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |