Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108552 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CNR1CNR2TRPV1DAGLA | |
| SCHEMBL7109263 | 0.87 | TRPV1 (0.49) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL24627503 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CNR1CNR2TRPV1 | |
| SCHEMBL7108549 | 0.79 | CNR1 (0.62) | ALDH1A1CNR1CNR2FAAHMAPT | |
| SCHEMBL9751428 | 0.77 | FAAH (0.50) | ALDH1A1CNR1CNR2TRPV1FAAH | |
| SCHEMBL2901524 | 0.77 | FAAH (0.50) | ALDH1A1CNR1CNR2TRPV1FAAH | |
| SCHEMBL8431397 | 0.77 | FAAH (0.50) | ALDH1A1CNR1CNR2TRPV1FAAH | |
| SCHEMBL13571362 | 0.77 | FAAH (0.50) | ALDH1A1CNR1CNR2TRPV1FAAH | |
| SCHEMBL24627498 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CNR1CNR2TRPV1MAPT | |
| SCHEMBL23017057 | 0.75 | ALDH1A1 (0.51) | ALDH1A1CNR1CNR2TRPV1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066235-B1 | SYNTHETIC ENDOGENOUS CANNABINOID ANALOGUES AND USES THEREOF | YISSUM RES DEV CO (IL) | 2003-10-01 | — | — | EP | claimed |
| US-6531636-B1 | Derivatives of 2-archidonoyl glycerol, stable to hydrolysis; ethers derived from long chain fatty alcohols (archidonyl alcohol) bind to the CB1 and CB2 cannabinoid receptors; in vivo effects similar to anandamide and 2-Ara-Gl | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-03-11 | — | — | US | claimed |
| EP-1066235-B1 | SYNTHETIC ENDOGENOUS CANNABINOID ANALOGUES AND USES THEREOF | YISSUM RES DEV CO (IL) | 2003-10-01 | — | — | EP | disclosed |
| US-6531636-B1 | Derivatives of 2-archidonoyl glycerol, stable to hydrolysis; ethers derived from long chain fatty alcohols (archidonyl alcohol) bind to the CB1 and CB2 cannabinoid receptors; in vivo effects similar to anandamide and 2-Ara-Gl | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-03-11 | — | — | US | disclosed |