SCHEMBL7109374

SCHEMBL7109374

CC(=O)c1c(C)cc2c(c1C)C(C)=C(C)C2(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.37
THRB P10828 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009728 0.76
SCHEMBL2810235 0.69 CYP3A4 (0.44) THRBCYP3A4
SCHEMBL7953582 0.65 CYP3A4 (0.44) THRBCYP3A4
SCHEMBL7084327 0.65 TDP2 (0.35)
SCHEMBL13668279 0.63 CYP26A1 (0.32)
SCHEMBL2381170 0.61 SMN1; SMN2 (0.42) THRBCYP3A4
SCHEMBL18493977 0.61 HPGD (0.39) CYP3A4
SCHEMBL15448023 0.61 ALDH1A1 (0.39) THRBCYP3A4
SCHEMBL19570319 0.61 THRB (0.40) THRBCYP3A4
SCHEMBL19334322 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390337-A1 PRECURSORS FOR KETONES AND ALDEHYDES Givaudan SA (CH) 2004-02-25 EP disclosed
WO-2002096850-A1 PRECURSORS FOR KETONES AND ALDEHYDES GIVAUDAN SA (CH) 2002-12-05 WO disclosed