Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111534 | 0.96 | SLC6A2 (0.37) | HSD11B1RARBTLR8DRD2SLC6A2 | |
| SCHEMBL7108905 | 0.96 | SLC6A2 (0.37) | HSD11B1RARBTLR8DRD2SLC6A2 | |
| SCHEMBL7103915 | 0.96 | HSD11B1 (0.33) | HSD11B1RARBPSMB5BRS3TLR8 | |
| SCHEMBL7109568 | 0.96 | TLR8 (0.31) | HSD11B1RARBPSMB5TLR8 | |
| SCHEMBL7109434 | 0.95 | SLC6A2 (0.37) | HSD11B1RARBTLR8DRD2SLC6A2 | |
| SCHEMBL7105397 | 0.94 | EDNRB (0.32) | PSMB5TLR8 | |
| SCHEMBL7108748 | 0.92 | SLC6A2 (0.37) | HSD11B1RARBTLR8DRD2SLC6A2 | |
| SCHEMBL7110770 | 0.92 | HSD11B1 (0.34) | HSD11B1RARBTLR8DRD2SLC6A2 | |
| SCHEMBL7109747 | 0.90 | ADORA3 (0.30) | — | |
| SCHEMBL7111659 | 0.90 | DRD2 (0.34) | HSD11B1RARBTLR8DRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |