Formic Acid

Formic Acid

SCHEMBL7109456

O=CO.Oc1ccc2c(c1)OCO2

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.80
ALDH1A1 P00352 3/20 0.55
HSD17B10 Q99714 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
CALM1 P0DP23 2/20 0.49
MAPK1 P28482 1/20 0.48
MIF P14174 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
SRD5A2 P31213 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510426 0.89 CYP3A4 (1.00) CYP3A4ALDH1A1HSD17B10TDP1CALM1
SCHEMBL20959 0.89 CYP3A4 (1.00) CYP3A4ALDH1A1HSD17B10TDP1CALM1
Formaldehyde SCHEMBL27904688 0.88 CYP3A4 (0.87) CYP3A4ALDH1A1HSD17B10TDP1CALM1
Methane SCHEMBL4169772 0.87 CYP3A4 (0.95) CYP3A4ALDH1A1HSD17B10TDP1CALM1
Phosphoric Acid SCHEMBL2592727 0.84 CYP3A4 (0.80) CYP3A4ALDH1A1HSD17B10TDP1CALM1
Acetic Acid SCHEMBL28643630 0.82 CYP3A4 (0.77) CYP3A4ALDH1A1TDP1CALM1MAPK1
Catechol SCHEMBL5622502 0.80 CYP3A4 (0.80) CYP3A4ALDH1A1TDP1CALM1MAPK1
Alcohol SCHEMBL8027238 0.80 CYP3A4 (0.80) CYP3A4ALDH1A1CALM1MAPK1MEN1
SCHEMBL25351591 0.77 CYP3A4 (0.75) CYP3A4ALDH1A1CALM1MAPK1MEN1
SCHEMBL746125 0.76 CYP3A4 (0.74) CYP3A4ALDH1A1HSD17B10MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167365-B1 Method of producing sesamol formic acid ester and sesamol DAICEL CHEM (JP) 2003-10-22 EP disclosed
JP-2002138087-A SESAMOL FORMATE AND METHOD FOR PRODUCING THE SAME DAICEL CHEM IND LTD 2002-05-14 JP disclosed
US-6384247-B2 HELIOTROPIN OXIDIZED WITH A PERCARBOXYLIC ACID IN THE PRESENCE OF FORMIC ACID; BY-PRODUCT INHIBITION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-07 US disclosed
US-20020016479-A1 Method of producing sesamol formic acid ester and sesamol DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-02-07 US disclosed
EP-1167365-A1 Method of producing sesamol formic acid ester and sesamol DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016479-A1 Method of producing sesamol formic acid ester and sesamol HAO2, HCAR3, HAO1 CYP3A4 253/4885ALDH1A1 3347/4885HSD17B10 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.