Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.95 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510426 | 0.98 | CYP3A4 (1.00) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| SCHEMBL20959 | 0.98 | CYP3A4 (1.00) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| Formaldehyde SCHEMBL27904688 | 0.91 | CYP3A4 (0.87) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| Alcohol SCHEMBL8027238 | 0.87 | CYP3A4 (0.80) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| Phosphoric Acid SCHEMBL2592727 | 0.87 | CYP3A4 (0.80) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| Formic Acid SCHEMBL7109456 | 0.87 | CYP3A4 (0.80) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| Catechol SCHEMBL5622502 | 0.87 | CYP3A4 (0.80) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| Acetic Acid SCHEMBL28643630 | 0.86 | CYP3A4 (0.77) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| SCHEMBL25351591 | 0.84 | CYP3A4 (0.75) | CYP3A4CALM1ALDH1A1MAPK1MEN1 | |
| SCHEMBL746125 | 0.83 | CYP3A4 (0.74) | CYP3A4ALDH1A1MAPK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233913-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2009-09-17 | — | — | US | claimed |
| US-20090233913-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233913-A1 | OPTICAL ISOMERS OF DIHYDRO-2,3-BENZODIAZEPINES AND THEIR STEREOSELECTIVE SYNTHESIS | GABRA2, GABRA3, GABRB2 | CYP3A4 320/4885CALM1 905/4885ALDH1A1 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.