Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796968 | 0.87 | HTR2A (0.50) | MAPTTDP1KDM4EHTR2AHTR2C | |
| SCHEMBL29368415 | 0.87 | HTR2A (0.50) | MAPTTDP1KDM4EHTR2AHTR2C | |
| SCHEMBL8388479 | 0.85 | KDM4E (0.49) | MAPTTDP1KDM4EHTR2AHTR2C | |
| SCHEMBL27895036 | 0.85 | KDM4E (0.49) | MAPTTDP1KDM4EHTR2AHTR2C | |
| SCHEMBL8389017 | 0.82 | KDM4E (0.53) | MAPTTDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL8390992 | 0.80 | KDM4E (0.45) | MAPTTDP1KDM4EHTR2AHTR2C | |
| SCHEMBL6306446 | 0.80 | MAPT (0.45) | MAPTTDP1KDM4EHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL27561698 | 0.79 | ALDH1A1 (0.50) | MAPTTDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL12088427 | 0.78 | GPR35 (0.51) | MAPTTDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL28220718 | 0.78 | TSHR (0.57) | MAPTTDP1KDM4EHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315433-A | Low-free high-compatibility toluene diisocyanate trimer curing agent and preparation method thereof | UNIV SOUTH CHINA TECH | 2016-02-10 | — | — | CN | claimed |
| CN-102898816-A | Preparation method of moisture-permeable thermoplastic polyurethane elastomer | AUSTIN NOVEL MATERIALS ZHANGJIAGANG CO LTD | 2013-01-30 | — | — | CN | claimed |
| CN-105315433-A | Low-free high-compatibility toluene diisocyanate trimer curing agent and preparation method thereof | UNIV SOUTH CHINA TECH | 2016-02-10 | — | — | CN | disclosed |
| CN-102898816-A | Preparation method of moisture-permeable thermoplastic polyurethane elastomer | AUSTIN NOVEL MATERIALS ZHANGJIAGANG CO LTD | 2013-01-30 | — | — | CN | disclosed |
| EP-1353636-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002094208-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G - CLAIROL, INC. (US) | 2002-11-28 | — | — | WO | disclosed |
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | MAPT 3531/4885TDP1 1337/4885KDM4E 1715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.