Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723539 | 0.88 | PTGS2 (0.56) | PTGS2PTGS1PDE3A | |
| SCHEMBL6730025 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1PDE3AALDH1A1 | |
| SCHEMBL7116583 | 0.85 | PTGS2 (0.47) | PTGS2PTGS1PDE3AALDH1A1 | |
| SCHEMBL7115127 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1PDE3AALDH1A1 | |
| SCHEMBL7108676 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL6722721 | 0.82 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6718874 | 0.82 | PTGS2 (0.43) | PTGS2PTGS1PDE3AALDH1A1 | |
| SCHEMBL7110830 | 0.81 | PTGS2 (0.50) | PTGS2PTGS1FFAR4 | |
| SCHEMBL7110955 | 0.81 | MAPK14 (0.36) | PTGS2PTGS1FFAR4 | |
| SCHEMBL7110064 | 0.81 | PTGS2 (0.39) | PTGS2PTGS1PDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296971-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001081332-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2001-11-01 | — | — | WO | disclosed |