SCHEMBL7110619

SCHEMBL7110619

O=C(O)c1cccc(Oc2cccc(C(F)(F)F)c2)n1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.74
GAA P10253 3/20 0.50
L3MBTL1 Q9Y468 4/20 0.49
ALDH1A1 P00352 2/20 0.49
POLB P06746 1/20 0.49
KMO O15229 1/20 0.48
KDM4E B2RXH2 3/20 0.47
ABCG2 Q9UNQ0 1/20 0.47
MRGPRX4 Q96LA9 2/20 0.46
LRRK2 Q5S007 1/20 0.46
HSD17B14 Q9BPX1 1/20 0.46
ADORA2A P29274 1/20 0.46
NTRK1 P04629 1/20 0.46
NPSR1 Q6W5P4 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
RAB9A P51151 1/20 0.45
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569584 0.88 MAPT (0.73) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL8570351 0.88 MAPT (0.73) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL29607042 0.87 MAPT (0.65) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL8773158 0.87 MAPT (0.65) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL3841693 0.86 MAPT (0.75) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL7528425 0.85 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL8065139 0.84 MAPT (0.72) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL7108376 0.84 MAPT (0.58) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL7108274 0.84 MAPT (0.61) MAPTGAAL3MBTL1ALDH1A1POLB
SCHEMBL7108355 0.84 MAPT (0.61) MAPTGAAL3MBTL1KMOKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107382847-A A kind of synthetic method of fluorine metazachlor 南通嘉禾化工有限公司 2017-11-24 CN claimed
EP-0949248-B1 6-(NONSUBSTITUTED OR SUBSTITUTED) PHENOXYPICOLINIC ACIDS, PROCESS OF PREPARING THE SAME, AND AGRICULTURAL/HORTICULTURAL GERMICIDES CONTAINING THE SAME KUREHA CHEMICAL IND CO LTD (JP) 2003-10-08 EP disclosed
EP-0806414-B1 Intermediates for herbicidal carboxamide derivatives BASF AG (DE) 2002-06-12 EP disclosed
EP-1207154-A1 Herbicidal carboxamide derivatives BASF AKTIENGESELLSCHAFT (DE) 2002-05-22 EP disclosed
EP-0488474-B1 Herbicidal carboxamide derivatives BASF AG (DE) 2002-04-17 EP disclosed
US-6200933-B1 LOW TOXICITY TO HUMANS AND CATTLE KUREHA KAGAKU KABUSHIKI KAISHA (JP) 2001-03-13 US disclosed
US-6159901-A 6-phenoxy picolinic acid alkylidene hydrazide derivative, process for producing the same and herbicide using the same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-12-12 US disclosed
US-6127390-A ANTITUMOR AGENTS INHIBITING FARNESYL-PROTEIN TRANSFERASE, FOR TREATING CANCER MERCK & CO., INC. (US) 2000-10-03 US disclosed
EP-1020444-A1 6-PHENOXYPICOLINIC ACID, ALKYLIDENEHYDRAZIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed
EP-0949248-A1 6-(NONSUBSTITUTED OR SUBSTITUTED) PHENOXYPICOLINIC ACIDS, PROCESS OF PREPARING THE SAME, AND AGRICULTURAL/HORTICULTURAL GERMICIDES CONTAINING THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-10-13 EP disclosed
EP-0447004-B1 Herbicidal carboxamide derivatives SHELL INT RESEARCH (NL) 1998-01-28 EP disclosed
EP-0806414-A1 Intermediates for herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-11-12 EP disclosed
US-5384305-A Plant growth regulators SHELL RESEARCH LIMITED (GB) 1995-01-24 US disclosed
US-5294597-A 2-((Halophenyl)amido-)m,6-((halophenyl)oxy-)pyridines SHELL RESEARCH LIMITED (GB) 1994-03-15 US disclosed
EP-0488474-A1 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-06-03 EP disclosed
EP-0447004-A2 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-18 EP disclosed