Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113786 | 0.84 | KCNH2 (0.31) | GABRA1GABRB2KCNH2GRIN2BPDE3B | |
| SCHEMBL6858942 | 0.79 | GABRA1 (0.41) | ADRA2AGABRA1GABRB2ADRB3ADRB1 | |
| SCHEMBL6859341 | 0.70 | GCGR (0.34) | GABRA1GABRB2RORC | |
| SCHEMBL7115301 | 0.68 | GAA (0.37) | GABRA1GABRB2ADRB3ADRB1ADRB2 | |
| SCHEMBL19760427 | 0.67 | CYP19A1 (0.41) | GABRA1GABRB2ADRB3ADRB1RORC | |
| SCHEMBL6859347 | 0.67 | DPP4 (0.32) | RORC | |
| SCHEMBL8227727 | 0.66 | IDO1 (0.48) | GABRA1GABRB2 | |
| SCHEMBL21900429 | 0.64 | TRPA1 (0.39) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8349146 | 0.64 | CTSS (0.42) | GABRA1GABRB2 | |
| SCHEMBL9734205 | 0.64 | GABRA1 (0.50) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638646-B2 | Polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | SEMICONDUCTORS GMBH (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030088050-A1 | Substituted poly(arylenevinylenes), process for their preparation, and their use in electroluminescent elements | MERCK PATENT GMBH (DE) | 2003-05-08 | — | — | US | disclosed |
| US-20020064680-A1 | Substituted poly(arylene vinylenes), method for producing the same, and their use in electroluminescent elements | AXIVA GMBH (DE) | 2002-05-30 | — | — | US | disclosed |