SCHEMBL711085

SCHEMBL711085

CC(C)(C)NS(=O)(=O)c1cccs1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
ALDH1A1 P00352 4/20 0.54
MAPT P10636 1/20 0.54
CACNA1B Q00975 1/20 0.54
APBA1 Q02410 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HPGD P15428 3/20 0.49
TP53 P04637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
HTT P42858 1/20 0.47
NPC1 O15118 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GLA P06280 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825084 0.92 CYP2D6 (0.49) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
Toluene SCHEMBL28291699 0.85 HPGD (0.48) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL1164889 0.78 CYP2D6 (0.62) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL24254325 0.77 CYP2D6 (0.67) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL30517142 0.75 CYP2D6 (0.50) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL1863910 0.74 CYP2D6 (0.62) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL8232303 0.74 CYP2D6 (0.62) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL4433902 0.74 CYP2D6 (0.62) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL7455235 0.74 CYP2D6 (0.62) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL855231 0.74 L3MBTL1 (0.56) CYP2D6CYP2C9CYP2C19ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119447465-A Electrolyte and application thereof in double-ion battery 广西师范大学 2025-02-14 CN claimed
CN-121885770-A Lithium ion battery and power utilization device 深圳市豪鹏科技股份有限公司 2026-04-17 CN disclosed
CN-119447465-A Electrolyte and application thereof in double-ion battery 广西师范大学 2025-02-14 CN disclosed
CN-116487696-A Nonaqueous electrolyte, lithium ion battery, battery module, battery pack, and power utilization device 上海如鲲新材料股份有限公司 2023-07-25 CN disclosed
US-20210024498-A1 TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF MEDICONNS SHANGHAI BIOPHARMACEUTICAL CO LTD (CN) 2021-01-28 US disclosed
CN-109715615-A Biaryl methyl heterocycles 蒙特利尔大学 2019-05-03 CN disclosed
US-9422271-B2 Pyrimidine compounds as tuberculosis inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2016-08-23 US disclosed
EP-1869009-B1 NEW BICYCLIC ANGIOTENSIN II AGONISTS VICORE PHARMA AB (SE) 2016-06-01 EP disclosed
US-9139609-B2 C-4″ position substituted macrolide derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-09-22 US disclosed
US-20140249137-A1 PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2014-09-04 US disclosed
US-5585377-A CONTROLLING INTRAOCULAR PRESSURE ALCON LABORATORIES, INC. (US) 1996-12-17 US disclosed
US-5444067-A Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety MERCK & CO., INC. (US) 1995-08-22 US disclosed
US-5378703-A FOR CONTROLLING INTRAOCULAR PRESSURE ALCON LABORATORIES, INC. (US) 1995-01-03 US disclosed
US-5240923-A Treating glaucoma ALCON LABORATORIES, INC. (US) 1993-08-31 US disclosed
EP-0527801-A4 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS 1993-03-10 EP disclosed
EP-0527801-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1993-02-24 EP disclosed
US-5153192-A For controlling intraocular pressure ALCON LABORATORIES, INC. (US) 1992-10-06 US disclosed
WO-1991015486-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1991-10-17 WO disclosed
US-4756742-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-12 US disclosed
CN-85101667-A The aminosulfonylthiophene compound that replaces and the preparation method of its esters and as the purposes of weedicide 1987-01-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024498-A1 TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF PRLHR, DRD2, AVPR2 CYP2D6 556/4885CYP2C9 1930/4885CYP2C19 719/4885
US-20140249137-A1 PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS TYMS, TYMP, DPYD CYP2D6 862/4885CYP2C9 1789/4885CYP2C19 1903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.