Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110717 | 0.86 | PTGDR2 (0.42) | LCKKMT2AMEN1MAPKAPK2PTGER1 | |
| SCHEMBL7110984 | 0.82 | NLRP3 (0.42) | NLRP3SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL8234810 | 0.79 | SMN1; SMN2 (0.41) | NLRP3SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL5692965 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1POLBMAPT | |
| SCHEMBL7110406 | 0.79 | LCK (0.48) | LCKMAPKAPK2PTGER1ATR | |
| SCHEMBL3742052 | 0.79 | RAB9A (0.44) | NLRP3SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL29498073 | 0.77 | ATR (0.47) | LCKKMT2AMEN1MAPKAPK2ATR | |
| SCHEMBL16925304 | 0.77 | ATR (0.47) | LCKKMT2AMEN1MAPKAPK2ATR | |
| SCHEMBL29223295 | 0.77 | MAPKAPK2 (0.34) | MAPKAPK2MAPTL3MBTL1 | |
| SCHEMBL2871142 | 0.77 | NAMPT (0.46) | MKNK2SMN1; SMN2POLBMAPTPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158218-A1 | Thrombin inhibitors | NANTERMET PHILIPPE G (US) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158218-A1 | Thrombin inhibitors | F2, SERPINC1, TFPI | NLRP3 3206/4885LCK 3358/4885MKNK2 3571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.