Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942181 | 0.81 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL2687014 | 0.78 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL5837265 | 0.78 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL2043313 | 0.78 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8060281 | 0.75 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8971039 | 0.75 | PNMT (0.46) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8861800 | 0.74 | PNMT (0.54) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7877087 | 0.74 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6651972 | 0.74 | PNMT (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6651980 | 0.74 | PNMT (0.40) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349822-A1 | FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055463-A1 | FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-18 | — | — | WO | disclosed |