Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304100 | 0.83 | HDAC8 (0.47) | HDAC8CYP2D6CYP2C19CA1CA2 | |
| Hydrochloric Acid SCHEMBL6892436 | 0.82 | HDAC8 (0.46) | HDAC8CYP2D6CYP2C19CA1CA2 | |
| SCHEMBL721359 | 0.74 | CYP2D6 (0.40) | CYP2D6CYP2C19CA1CA2KDM4E | |
| Bromide SCHEMBL11215457 | 0.71 | ALDH1A1 (0.45) | CYP2D6CYP2C19CA1CA2KDM4E | |
| Hydrochloric Acid SCHEMBL7005196 | 0.71 | KDM4E (0.49) | CYP2D6CYP2C19CA1CA2KDM4E | |
| SCHEMBL16469874 | 0.70 | HDAC8 (0.52) | HDAC8KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1425987 | 0.69 | CYP2D6 (0.44) | CYP2D6CYP2C19KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4035922 | 0.69 | HDAC8 (0.50) | HDAC8KDM4EALDH1A1SMN1; SMN2HTT | |
| Bromide SCHEMBL7608010 | 0.69 | HDAC8 (0.50) | HDAC8KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2732035 | 0.67 | CYP2D6 (0.41) | CYP2D6CYP2C19CA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010741-B1 | Electrochromic device | NIPPON MITSUBISHI OIL CORP (JP) | 2003-10-15 | — | — | EP | claimed |