Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11725090 | 0.80 | KDM4E (0.45) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14740720 | 0.74 | CALM1 (0.44) | KDM4EALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7111181 | 0.74 | HDAC8 (0.40) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7005196 | 0.73 | KDM4E (0.49) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL11215457 | 0.73 | ALDH1A1 (0.45) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17130344 | 0.69 | TP53 (0.44) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL11692702 | 0.68 | TP53 (0.48) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10730872 | 0.67 | TDP1 (0.48) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12558271 | 0.67 | CYP2D6 (0.46) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17968399 | 0.66 | KDM4E (0.38) | CYP2D6CYP2C19KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751577-B1 | A method of manufacturing a sterilized optical analyte sensor | MEDTRONIC MINIMED INC (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2989975-B1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9839378-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9757057-B2 | Dry insertion and one-point in vivo calibration of an optical analyte sensor | MEDTRONIC MINIMED, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9693720-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2769226-B1 | COMBINATIONS OF FLUORPHORES AND PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | MEDTRONIC MINIMED INC (US) | 2017-05-24 | — | — | EP | disclosed |
| EP-2534470-B1 | ANTIOXIDANT PROTECTION OF A CHEMICAL SENSOR | MEDTRONIC MINIMED INC (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-2989975-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | Medtronic MiniMed, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-2916722-A1 | DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR | Medtronic MiniMed, Inc. (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2222686-B1 | POLYVIOLOGEN BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | MEDTRONIC MINIMED INC (US) | 2015-06-17 | — | — | EP | disclosed |
| WO-2008097747-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | GLUMETRICS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080188725-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188722-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-04-20 | — | — | US | disclosed |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-02-12 | — | — | US | disclosed |
| US-6627177-B2 | Obtaining flurorophore dye which is compatible with the analyte solution; combining withboronic acid-containing quencher molecule; contacting with excitation light source coupled with a detector; producing signal; quantification | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-30 | — | — | US | disclosed |
| EP-1340076-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | The Regents of the University of California (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046752-A9 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020106326-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof | CALIFORNIA, UNIVERSITY OF THE REGENTS OF THE | 2002-08-08 | — | — | US | disclosed |
| WO-2002046752-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, BLVRB, FOSB | CYP2D6 731/4885CYP2C19 2561/4885KDM4E 2992/4885 |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, FOSB, BLVRB | CYP2D6 774/4885CYP2C19 2529/4885KDM4E 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.