Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7005196

[Cl-].[Cl-].c1ccc(C[n+]2ccccc2-[n+]2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.41
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 5/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HPGD P15428 3/20 0.49
NPC1 O15118 2/20 0.49
HTT P42858 2/20 0.49
MITF O75030 1/20 0.49
GLA P06280 1/20 0.49
GAA P10253 1/20 0.49
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
BCHE P06276 1/20 0.37
CHKA P35790 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11215457 0.96 ALDH1A1 (0.45) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL11363136 0.75 KDM4E (0.47) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL15153589 0.73 SMN1; SMN2 (0.34) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL29754142 0.73 RAB9A (0.52) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL637319 0.73 RAB9A (0.52) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL11363133 0.73 KDM4E (0.46) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
Iodide SCHEMBL8962414 0.73 KDM4E (0.44) KDM4EALDH1A1RAB9ASMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL6653866 0.73 CYP2D6 (0.50) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL721359 0.73 CYP2D6 (0.40) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL11725090 0.72 KDM4E (0.45) KDM4EALDH1A1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6657768-B2 Ion conductive layer formed by curing an ethenically unsaturated bipyridinium compound, an unsaturated metallocene such as vinylferrocene, and a solid electrolyte precursor such as a polyoxyalkylene glycol mono- or di- (meth)acrylate NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-12-02 US disclosed
EP-1010741-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2003-10-15 EP disclosed
EP-0995786-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2003-01-08 EP disclosed
US-20020136898-A1 Electrochromic device NIPPON MITSUBISHI OIL CORPORATION 2002-09-26 US disclosed
US-6208452-B1 HAS AN ION CONDUCTIVE LAYER OBTAINED BY CURING A COMPOSITION COMPRISING A BIPYRIDINIUM COMPOUND, A SPECIFIC AMINE COMPOUND AND A PRECURSOR COMPONENT OF A POLYMERIC SOLID ELECTROLYTE DISPOSED BETWEEN TWO ELECTRICALLY CONDUCTIVE SUBSTRATES NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-27 US disclosed
EP-1010741-A2 Electrochromic device Nippon Mitsubishi Oil Corporation (JP) 2000-06-21 EP disclosed
EP-0995786-A1 Electrochromic device Nippon Mitsubishi Oil Corporation (JP) 2000-04-26 EP disclosed