Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108369 | 0.85 | FAAH (0.65) | NPC1RAB9AALDH1A1FAAHMAPT | |
| SCHEMBL7112061 | 0.83 | FAAH (0.64) | NPC1RAB9AALDH1A1FAAHMAPT | |
| SCHEMBL7112070 | 0.83 | NPC1 (0.61) | NPC1RAB9AALDH1A1FAAHMAPT | |
| SCHEMBL27652942 | 0.82 | NPC1 (0.83) | NPC1RAB9AALDH1A1FAAHLMNA | |
| SCHEMBL10245207 | 0.79 | NPC1 (0.67) | NPC1RAB9AALDH1A1FAAHLMNA | |
| SCHEMBL19231603 | 0.77 | NPC1 (0.60) | NPC1RAB9AALDH1A1FAAHLMNA | |
| SCHEMBL178450 | 0.76 | NPC1 (0.73) | NPC1RAB9AALDH1A1FAAHLMNA | |
| SCHEMBL6037506 | 0.76 | RAB9A (0.96) | NPC1RAB9AALDH1A1HTTTSHR | |
| SCHEMBL5546588 | 0.76 | NPC1 (0.58) | NPC1RAB9AALDH1A1FAAHMAPT | |
| SCHEMBL5546599 | 0.76 | NPC1 (0.58) | NPC1RAB9AALDH1A1FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030170173-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2003-09-11 | — | — | US | disclosed |
| EP-1283728-A2 | CONTRAST AGENTS | Amersham Health AS (NO) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001089584-A2 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030170173-A1 | Contrast agents | GBA1, RNASE1, MAN2B1 | NPC1 345/4885RAB9A 1184/4885ALDH1A1 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.