Acrylic Acid

Acrylic Acid

SCHEMBL7112943

C=C(CCC(O)CO)C(=O)O.C=CC(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 1/20 0.37
TET2 Q6N021 5/20 0.35
TET3 O43151 1/20 0.35
TET1 Q8NFU7 1/20 0.35
THRB P10828 1/20 0.33
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243507 0.90 TET2 (0.41) ALOX15HSD17B10LMNATET2TET3
Water SCHEMBL10629808 0.88 TET2 (0.40) ALOX15HSD17B10LMNATET2TET3
Acrylonitrile SCHEMBL2143938 0.84 TET2 (0.32) ALOX15HSD17B10TET2TET3TET1
Acrylic Acid SCHEMBL5469059 0.81 ALOX15 (0.50) ALOX15HSD17B10LMNATET2TET3
Acrylic Acid SCHEMBL28688725 0.81 ALOX15 (0.50) ALOX15HSD17B10LMNATET2TET3
SCHEMBL164149 0.79 TET2 (0.39) LMNATET2TET3TET1THRB
Acrylic Acid SCHEMBL11323515 0.78 THRB (0.59) ALOX15HSD17B10LMNATHRB
Acrylic Acid SCHEMBL8935013 0.78 THRB (0.59) ALOX15HSD17B10LMNATHRB
Glycerin SCHEMBL25331899 0.77 LMNA (0.56) ALOX15HSD17B10LMNATHRB
Glycerin SCHEMBL116158 0.77 LMNA (0.56) ALOX15HSD17B10LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1357955-A1 DRUG DELIVERY FROM STENTS Biocompatibles UK Limited (GB) 2003-11-05 EP disclosed
EP-1357956-A1 STENS WITH DRUG-CONTAINING AMPHIPHILIC POLYMER COATING Biocompatibles UK Limited (GB) 2003-11-05 EP disclosed
WO-2002055122-A1 STENS WITH DRUG-CONTAINING AMPHIPHILIC POLYMER COATING BIOCOMPATIBLES UK LIMITED (GB) 2002-07-18 WO disclosed
WO-2002055121-A1 DRUG DELIVERY FROM STENTS BIOCOMPATIBLES UK LIMITED (GB) 2002-07-18 WO disclosed