SCHEMBL7112993

SCHEMBL7112993

CC(C=CCCO)(c1c(Cl)cc(O)cc1Cl)c1c(Cl)cc(O)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601524 0.71 ESR1 (0.43) CYP3A4HPGDHSD17B10
SCHEMBL10936836 0.68 HSD17B10 (0.50) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL6766429 0.68 HSD17B10 (0.50) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL11743331 0.63
SCHEMBL29295830 0.58 ALOX15 (0.39) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL26269781 0.57 HSD17B10 (0.37) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL5940300 0.57 HSD17B10 (0.52) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL23043288 0.57 HSD17B10 (0.41) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL4054790 0.57 HPGD (0.41) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL24663908 0.57 CYP3A4 (0.48) CYP3A4HPGDCRHBPCRHR2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4535048-A Toner for development of electrostatic charges CANON KABUSHIKI KAISHA (JP) 1985-08-13 US claimed
EP-0785476-B1 Heat fixing method and use of a heat fixable toner CANON KK (JP) 2003-04-23 EP disclosed
US-6120958-A AN AZO TYPE IRON COMPLEX PARTICLES FOR PHOTO DRY PROCESSING HODOGAYA CHEMICAL CO., LTD. (JP) 2000-09-19 US disclosed
EP-0977093-A2 Electrostatic image developing toner HODOGAYA CHEMICAL CO LTD (JP) 2000-02-02 EP disclosed
US-5814429-A Heat fixing method employing peelable film between heater and recording medium CANON KABUSHIKI KAISHA (JP) 1998-09-29 US disclosed
EP-0785476-A2 Heat fixing method and use of a heat fixable toner CANON KABUSHIKI KAISHA (JP) 1997-07-23 EP disclosed
US-5478686-A Fixable toner with a modified bisphenolic polyester resin CANON KABUSHIKI KAISHA (JP) 1995-12-26 US disclosed
EP-0373652-B1 Method of heat-fixing toner image CANON KK (JP) 1995-09-13 EP disclosed
EP-0421416-A2 Heat fixable toner and heat fixing method CANON KABUSHIKI KAISHA (JP) 1991-04-10 EP disclosed
US-4957774-A HEATING AND PRESSING THROUGH A FILM CONTACTING THE TONER IMAGE, CONTROLLING MELT VISCOSITY OF TONER CANON KABUSHIKI KAISHA (JP) 1990-09-18 US disclosed
EP-0373652-A2 Method of heat-fixing toner image CANON KABUSHIKI KAISHA (JP) 1990-06-20 EP disclosed
US-4868085-A LOW MELTING COPOLYESTER TONER CANON KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed