SCHEMBL7113261

SCHEMBL7113261

Cc1ccc(C)c(C(=O)P=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CSNK2A1 P68400 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
GAA P10253 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27698112 0.83 KMT2A (0.47) MEN1KMT2ACSNK2A1SMN1; SMN2MAPT
SCHEMBL2092006 0.78 MEN1 (0.53) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL9420245 0.78 MEN1 (0.57) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL9862051 0.78 MEN1 (0.57) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL501733 0.76 MEN1 (0.55) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL223101 0.76 CSNK2A1 (0.65) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL29636568 0.76 KMT2A (0.55) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL697905 0.76 KMT2A (0.55) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL6112904 0.74 MEN1 (0.53) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
Iodide SCHEMBL6113218 0.74 CSNK2A1 (0.63) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6818153-B2 Photocurable thermosetting luminescent resins BURNELL-JONES PETER (AU) 2004-11-16 US disclosed
WO-2004011571-A1 PHOTOCURABLE THERMOSETTING LUMINESCENT RESINS ORION 21 A. D. PTY LTD (AU) 2004-02-05 WO disclosed
US-20030085383-A1 For use as gel coat, laminating resin, casting resin or moldable resin; photoluminescent, thermoluminescent and electroluminescent properties BURNELL-JONES PETER (AU) 2003-05-08 US disclosed
US-5554666-A Photocurable compositions SUNREZ CORPORATION (US) 1996-09-10 US disclosed
US-5407972-A Improved sealants for air and marine vehicles SUNREZ CORP. (US) 1995-04-18 US disclosed