Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030373 | 0.88 | CYP3A4 (0.56) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL31290664 | 0.85 | CYP3A4 (0.50) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL3266396 | 0.84 | CYP3A4 (0.49) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL23158574 | 0.82 | ALDH1A1 (0.42) | PKMSMN1; SMN2CTBP2ALDH1A1KMT2A | |
| SCHEMBL6032361 | 0.81 | L3MBTL1 (0.47) | CYP3A4NPSR1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL30249949 | 0.81 | PKM (0.55) | PKMSMN1; SMN2CTBP2ALDH1A1TSHR | |
| SCHEMBL1107140 | 0.81 | PKM (0.55) | PKMSMN1; SMN2CTBP2ALDH1A1TSHR | |
| SCHEMBL878244 | 0.81 | CYP3A4 (0.49) | CYP3A4NPSR1PKMSMN1; SMN2CTBP2 | |
| SCHEMBL8973261 | 0.81 | ALDH1A1 (0.58) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL11128484 | 0.79 | CYP3A4 (0.47) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101012314-B | Optical anisotropy thin film and display device containing same | LG CHEMICAL CO., LTD. (KR) | 2011-12-28 | — | — | CN | disclosed |
| CN-100347207-C | Method for polymerizing cycloolefin polymer having polar functional group and electronic device using the polymerized cycloolefin | LG CHEMICAL LTD (KR) | 2007-11-07 | — | — | CN | disclosed |
| CN-101012314-A | Optical anisotropy thin film and display device containing same | LG CHEMICAL LTD (KR) | 2007-08-08 | — | — | CN | disclosed |
| CN-1692131-A | Method for polymerizing cycloolefin polymer having polar functional group and electronic device using the polymerized cycloolefin | LG CHEMICAL LTD (KR) | 2005-11-02 | — | — | CN | disclosed |
| US-20040162286-A1 | Substituted 6-(2-tolyl)-triazolopyrimidines as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | US | disclosed |
| EP-1412359-A1 | SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003008417-A9 | SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AG (DE) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003008417-A1 | SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162286-A1 | Substituted 6-(2-tolyl)-triazolopyrimidines as fungicides | CBR3, CBR1, TH | CYP3A4 339/4885NPSR1 2564/4885PKM 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.