Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 6/20 | 1.00 |
| ▸ | PLG | P00747 | 1/20 | 0.69 |
| ▸ | PROC | P04070 | 1/20 | 0.69 |
| ▸ | KLK1 | P06870 | 1/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303558 | 0.92 | F10 (0.84) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL7478524 | 0.91 | F10 (1.00) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL6303168 | 0.87 | F10 (0.77) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL6296950 | 0.84 | F10 (0.85) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL7450111 | 0.83 | F10 (0.72) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL14132298 | 0.82 | PRSS1 (0.69) | F10PRSS1 | |
| SCHEMBL7122855 | 0.81 | F10 (0.71) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL7406525 | 0.81 | F10 (0.77) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7476896 | 0.80 | F10 (0.79) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL7115966 | 0.80 | F10 (0.70) | F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | F10 60/4885PRSS1 34/4885PLG 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.