Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.71 |
| ▸ | PLG | P00747 | 2/20 | 0.68 |
| ▸ | KLK1 | P06870 | 2/20 | 0.68 |
| ▸ | PROC | P04070 | 1/20 | 0.68 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111879 | 0.89 | F10 (0.57) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7114694 | 0.88 | F10 (0.59) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7114685 | 0.88 | F10 (0.70) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7478524 | 0.83 | F10 (1.00) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7117254 | 0.83 | F10 (0.64) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7113702 | 0.81 | F10 (1.00) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7117722 | 0.80 | F10 (0.60) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7116303 | 0.79 | PRSS1 (0.59) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7123308 | 0.78 | F2 (0.64) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7119014 | 0.78 | F10 (0.72) | F10PRSS1PLGKLK1PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | F10 60/4885PRSS1 34/4885PLG 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.