Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | PARP1 | P09874 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894429 | 0.91 | KMT2A (0.66) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL1892934 | 0.86 | KMT2A (0.64) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL14157583 | 0.86 | KMT2A (0.69) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL14359359 | 0.84 | LMNA (0.71) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL6835723 | 0.84 | LMNA (0.88) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL11552814 | 0.84 | KMT2A (0.67) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL122684 | 0.84 | ALDH1A1 (0.71) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL29550999 | 0.84 | ALDH1A1 (0.71) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL11547493 | 0.84 | KDM4E (0.66) | LMNAKMT2AMEN1MAPTNR1I2 | |
| SCHEMBL7325672 | 0.83 | PARP1 (0.60) | LMNAKMT2AMEN1MAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |
| US-4742083-A | Method of relieving pain and inflammatory conditions employing substituted salicylamides | LEVER BROTHERS COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4725590-A | SKIN DISORDERS; ANTIACNE SHAMPOO AND SOAP | LEVER BROTHERS COMPANY (US) | 1988-02-16 | — | — | US | disclosed |
| US-4560549-A | TOPICAL AND SYSTEMICAL; HUMANS ANIMALS; MICROBIOCIDES | LEVER BROTHERS COMPANY (US) | 1985-12-24 | — | — | US | disclosed |