Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537822 | 0.86 | MAPT (0.62) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL1894429 | 0.85 | KMT2A (0.66) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL15525445 | 0.84 | MAPT (0.60) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL489857 | 0.83 | ALDH1A1 (0.48) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL7114649 | 0.83 | LMNA (0.69) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL3825061 | 0.82 | KDM4E (0.63) | PARP1MAPTKMT2AHTTLMNA | |
| Ethenzamide SCHEMBL25624 | 0.82 | MAPT (0.68) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL11202523 | 0.82 | KDM4E (0.63) | PARP1MAPTKMT2AHTTLMNA | |
| SCHEMBL3455066 | 0.82 | HTT (0.77) | PARP1MAPTKMT2AHTTLMNA | |
| Ethenzamide SCHEMBL27612766 | 0.82 | MAPT (0.68) | PARP1MAPTKMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614727-B1 | N-Nonanoylvanillylamine as an appetite reduction agent and as a means for generating the feeling of being full and corresponding orally consumable products and method | SYMRISE AG (DE) | 2016-09-07 | — | — | EP | disclosed |
| EP-2614727-A1 | N-Nonanoylvanillylamine as an appetite reduction agent, as a means for generating the feeling of being full and as a mood enhancer and corresponding material mixtures, orally consumable products and method | Symrise AG (DE) | 2013-07-17 | — | — | EP | disclosed |
| EP-0271059-B1 | 2-Methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-10-20 | — | — | EP | disclosed |
| US-4971984-A | Cardiovascular disorders, hypotensive agints | BEEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |