Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058078 | 0.88 | DRD2 (0.56) | DRD3DRD2ADRA1ADRD4RAB9A | |
| SCHEMBL7051851 | 0.88 | DRD3 (0.49) | DRD3DRD2DRD4TP53PKM | |
| SCHEMBL7053551 | 0.87 | DRD2 (0.45) | DRD3DRD2ADRA1ATP53ALDH1A1 | |
| SCHEMBL7115347 | 0.86 | DRD3 (0.49) | DRD3DRD2ADRA1ADRD4TP53 | |
| Hydrochloric Acid SCHEMBL7059854 | 0.86 | CCR3 (0.51) | DRD3DRD2ADRA1ADRD4CCR3 | |
| SCHEMBL7056847 | 0.83 | DRD2 (0.49) | DRD3DRD2ADRA1ADRD4TP53 | |
| SCHEMBL7119593 | 0.82 | CCR3 (0.55) | DRD3DRD2ADRA1ACCR3UBE2M | |
| SCHEMBL7060979 | 0.81 | DRD2 (0.52) | DRD3DRD2ADRA1ADRD4CCR3 | |
| SCHEMBL7055659 | 0.81 | DRD2 (0.50) | DRD3DRD2ADRA1ACCR3UBE2M | |
| SCHEMBL7118079 | 0.81 | DRD2 (0.46) | DRD3DRD2DRD4TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |