Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348651 | 0.80 | LMNA (0.56) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL3673972 | 0.78 | LMNA (0.50) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL4345481 | 0.77 | LMNA (0.56) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL10577183 | 0.77 | ALDH1A1 (0.67) | GAALMNAALDH1A1CREBBPTSHR | |
| SCHEMBL11808524 | 0.75 | LMNA (0.53) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL65969 | 0.73 | LMNA (0.64) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL8537334 | 0.73 | LMNA (0.64) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL29355285 | 0.73 | LMNA (0.64) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL8883810 | 0.71 | LMNA (0.61) | GAALMNAL3MBTL1ALDH1A1CREBBP | |
| Simazine SCHEMBL8409822 | 0.71 | LMNA (1.00) | GAALMNAL3MBTL1PDE4ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429612-A1 | HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE | Bayer CropScience AG (DE) | 2004-06-23 | — | — | EP | claimed |
| WO-2003026426-A1 | HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE | BAYER CROPSCIENCE AG (DE) | 2003-04-03 | — | — | WO | claimed |
| EP-0784431-A1 | SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL | BAYER AG (DE) | 1997-07-23 | — | — | EP | claimed |
| WO-1996010333-A1 | SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | claimed |
| US-5051125-A | S-ethyl cyclohexylethyl thiocarbamate and 2-chloro-4-(ethylamino)-6-(2-cyanoisopropylamino)-s-triazine | ICI AMERICAS INC. (US) | 1991-09-24 | — | — | US | claimed |
| EP-0184870-A1 | Synergistic herbicidal composition | STAUFFER CHEMICAL COMPANY (US) | 1986-06-18 | — | — | EP | claimed |
| US-5051125-A | S-ethyl cyclohexylethyl thiocarbamate and 2-chloro-4-(ethylamino)-6-(2-cyanoisopropylamino)-s-triazine | ICI AMERICAS INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0184870-A1 | Synergistic herbicidal composition | STAUFFER CHEMICAL COMPANY (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0182740-A2 | Synergistic agents and method for the selective control of weeds, particularly in cereal crops | CIBA-GEIGY AG (CH) | 1986-05-28 | — | — | EP | disclosed |
| US-4581434-A | USING DIFUNCTION COUPLING MEMBER TO LINK PESTICIDE TO A POLYETHER | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-08 | — | — | US | disclosed |