Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417046 | 0.90 | ABCB1 (1.00) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7119192 | 0.90 | ABCG2 (0.81) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL20339678 | 0.87 | ABCG2 (0.78) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL24614952 | 0.86 | ABCG2 (1.00) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL10335360 | 0.86 | ABCB1 (0.80) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL1627832 | 0.84 | KDM4E (0.82) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL3958745 | 0.84 | ABCG2 (0.72) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL28431125 | 0.83 | ABCG2 (0.73) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL31723172 | 0.83 | ABCG2 (0.73) | ABCG2ABCB1KDM4EMEN1ALDH1A1 | |
| 3,7-Dimethoxyflavone SCHEMBL4278796 | 0.83 | ALDH1A1 (1.00) | ABCG2ABCB1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | claimed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | claimed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | claimed |
| CN-111825364-B | Preparation method of environment-friendly naphthalene water reducer | 安徽鑫固环保股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-111825364-A | Preparation method of environment-friendly naphthalene water reducer | 安徽鑫固环保股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111807738-A | Additive for geopolymer | 安徽鑫固环保股份有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111808641-A | Novel water-coal-slurry dispersant and preparation method thereof | 萧县沃德化工科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111808651-A | 2-naphthol distillation residue modified coal water slurry dispersing agent and preparation method thereof | 萧县沃德化工科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111792867-A | Naphthalene water reducer containing distillation residues | 萧县沃德化工科技有限公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-111792868-A | Environment-friendly naphthalene-based high-efficiency water reducing agent and preparation method thereof | 萧县沃德化工科技有限公司 | 2020-10-20 | — | — | CN | disclosed |
| US-20170071902-A1 | NOX INHIBITOR AND NFkB INHIBITOR CONTAINING METHOXYFLAVONE | SUNTORY HOLDINGS LIMITED (JP) | 2017-03-16 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | disclosed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170071902-A1 | NOX INHIBITOR AND NFkB INHIBITOR CONTAINING METHOXYFLAVONE | NOX1, NFKBIA, NOX5 | ABCG2 4110/4885ABCB1 1908/4885KDM4E 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.