Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fisetin Tetramethyl Ether SCHEMBL7116147 | 0.90 | ABCG2 (1.00) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL3958745 | 0.89 | ABCG2 (0.72) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL5432990 | 0.88 | ABCG2 (0.78) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL25197634 | 0.85 | CYP3A4 (0.72) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| 3,7-Dimethoxyflavone SCHEMBL4278796 | 0.85 | ALDH1A1 (1.00) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL1627832 | 0.84 | KDM4E (0.82) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL20464068 | 0.80 | ADORA3 (1.00) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL29864461 | 0.80 | ADORA3 (1.00) | ABCG2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL6555693 | 0.80 | PABPC1 (0.76) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| Combretol SCHEMBL20220721 | 0.79 | ABCG2 (0.80) | ABCG2KDM4EALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-2024232198-A1 | AUTOPHAGY ACTIVATOR AND COMPOSITION FOR AUTOPHAGY ACTIVATION | 丸善製薬株式会社 | 2024-11-14 | — | — | WO | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |