Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627832 | 0.90 | KDM4E (0.82) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| 3,6-Dimethoxyflavone SCHEMBL4649913 | 0.89 | KDM4E (1.00) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL28566115 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL29768227 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL27726517 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL253523 | 0.85 | ABCG2 (1.00) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL29993383 | 0.85 | ABCG2 (1.00) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL15676588 | 0.85 | KDM4E (0.85) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL1534565 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4ECYP3A4MAPTHPGD | |
| SCHEMBL7119192 | 0.85 | ABCG2 (0.81) | ALDH1A1KDM4ECYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080846-A1 | COMPOSITION FOR PREVENTING OR TREATING FIBROSIS, COMPRISING FLAVONE | 서울대학교병원 | 2022-04-21 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| WO-2022080846-A1 | COMPOSITION FOR PREVENTING OR TREATING FIBROSIS, COMPRISING FLAVONE | 서울대학교병원 | 2022-04-21 | — | — | WO | disclosed |
| WO-2022080846-A1 | COMPOSITION FOR PREVENTING OR TREATING FIBROSIS, COMPRISING FLAVONE | 서울대학교병원 | 2022-04-21 | — | — | WO | disclosed |
| WO-2022080846-A1 | COMPOSITION FOR PREVENTING OR TREATING FIBROSIS, COMPRISING FLAVONE | 서울대학교병원 | 2022-04-21 | — | — | WO | disclosed |
| US-20180042899-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-15 | — | — | US | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| US-20140050694-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-20 | — | — | US | disclosed |
| CN-103547250-A | Novel application of flavonoid compound | UNIV YONSEI IACF | 2014-01-29 | — | — | CN | disclosed |
| US-20090269772-A1 | SYSTEMS AND METHODS FOR IDENTIFYING COMBINATIONS OF COMPOUNDS OF THERAPEUTIC INTEREST | THERASIS, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-06-04 | — | — | US | disclosed |
| WO-2008141074-A1 | IDENTIFICATION OF COMPOUNDS THAT PROTECT AGAINST AMYLOID DISEASES | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-11-20 | — | — | WO | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | ALDH1A1 2440/4885KDM4E 2309/4885CYP3A4 3010/4885 |
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PC, PCK2, CS | ALDH1A1 860/4885KDM4E 3739/4885CYP3A4 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.