⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714354 | 0.79 | — | — | |
| SCHEMBL28204890 | 0.79 | — | — | |
| SCHEMBL7121639 | 0.79 | — | — | |
| SCHEMBL28278700 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL15643833 | 0.77 | CYP2E1 (0.36) | — | |
| SCHEMBL9937418 | 0.76 | AOC1 (0.40) | — | |
| SCHEMBL21358990 | 0.76 | NOS2 (0.40) | — | |
| SCHEMBL2894382 | 0.74 | — | — | |
| SCHEMBL2896323 | 0.74 | — | — | |
| SCHEMBL5225727 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383915-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2024-11-21 | — | — | US | disclosed |
| EP-4320132-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117083279-A | Oxazepine compounds and their use in the treatment of cancer | 基因泰克公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2022216762-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2022-10-13 | — | — | WO | disclosed |
| US-20030109682-A1 | Maytansines and maytansine conjugates | SANTI DANIEL (US) | 2003-06-12 | — | — | US | disclosed |