Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 8/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116276 | 0.76 | — | — | |
| SCHEMBL17778292 | 0.74 | — | — | |
| SCHEMBL2894382 | 0.74 | — | — | |
| SCHEMBL2896323 | 0.74 | — | — | |
| SCHEMBL12988508 | 0.70 | CYP2A6 (0.40) | AOC1AOC3LOXL2 | |
| SCHEMBL2894657 | 0.70 | AOC1 (0.40) | AOC1AOC3LOXL2 | |
| SCHEMBL1416353 | 0.70 | CD274 (0.41) | AOC1AOC3LOXL2 | |
| SCHEMBL2888687 | 0.70 | AOC1 (0.35) | AOC1AOC3LOXL2 | |
| SCHEMBL9247760 | 0.67 | LOXL2 (0.35) | LOXL2 | |
| SCHEMBL2491544 | 0.67 | DPP4 (0.47) | AOC1AOC3LOXL2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10290819-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2019-05-14 | — | — | US | disclosed |
| US-20130284977-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012079741-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10290819-B2 | Metal complexes | PICALM, IMMT, IKZF3 | AOC1 1672/4885AOC3 2469/4885LOXL2 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.