Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886748 | 0.88 | MTNR1A (0.56) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14338249 | 0.81 | MTNR1B (0.69) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL171425 | 0.81 | MTNR1A (0.79) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29875454 | 0.81 | MTNR1A (0.79) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13488649 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18904875 | 0.80 | HDAC3 (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1CYP1A2 | |
| SCHEMBL16215583 | 0.79 | MTNR1A (0.58) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2534228 | 0.79 | GAA (0.58) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL359762 | 0.79 | MEN1 (0.71) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12722504 | 0.79 | MEN1 (0.63) | MTNR1AMTNR1BRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139442-A1 | Vasoactive agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1262195-A1 | VASOACTIVE AGENTS | Takeda Chemical Industries, Ltd. (JP) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139442-A1 | Vasoactive agents | VIPR2, VIPR1, GPR4 | MTNR1A 452/4885MTNR1B 282/4885RAB9A 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.