Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252778 | 0.81 | CHRM2 (0.38) | PIN1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6252269 | 0.80 | PIN1 (0.41) | PIN1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6254591 | 0.79 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2MEN1TP53 | |
| SCHEMBL6253854 | 0.76 | PIN1 (0.38) | PIN1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6255419 | 0.76 | PDE4B (0.31) | ALDH1A1 | |
| SCHEMBL6257935 | 0.75 | PIN1 (0.38) | PIN1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6256277 | 0.75 | TGFBR1 (0.42) | NPC1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6254810 | 0.74 | ALDH1A1 (0.36) | NPC1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6252284 | 0.73 | MAPT (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6258533 | 0.73 | SLC22A12 (0.38) | NPC1POLBRAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |