Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 7/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742545 | 0.89 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30563642 | 0.89 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9325576 | 0.87 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20358130 | 0.83 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29489189 | 0.83 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11734349 | 0.80 | SMN1; SMN2 (0.79) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6314314 | 0.79 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9183996 | 0.79 | LMNA (0.70) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL23464966 | 0.77 | LMNA (0.76) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL23705539 | 0.77 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |
| US-20030105137-A1 | Benzimidazole derivatives, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105137-A1 | Benzimidazole derivatives, processes for preparing them and their use as pharmaceutical compositions | CMA1, TPSD1, TPSAB1 | LMNA 1375/4885SMN1; SMN2 3071/4885MEN1 1573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.