Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195160 | 0.81 | MAPT (0.38) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8198856 | 0.78 | KDM4E (0.45) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL30032251 | 0.77 | NOS3 (0.44) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28861826 | 0.77 | KDM4E (0.43) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5657009 | 0.77 | KDM4E (0.43) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL24122438 | 0.77 | MAPT (0.44) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4704137 | 0.77 | NOS3 (0.44) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL15469493 | 0.77 | MAPT (0.43) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3504054 | 0.76 | ALDH1A1 (0.40) | MAPK1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4074890 | 0.76 | ALDH1A1 (0.44) | MAPK1MAPTALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353636-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002094208-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G - CLAIROL, INC. (US) | 2002-11-28 | — | — | WO | disclosed |