Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PPID | Q08752 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119570 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2TDP1PLA2G2CMAPTKDM4E | |
| SCHEMBL6692535 | 0.89 | MAPT (0.35) | SMN1; SMN2TDP1PLA2G2CMAPTPPID | |
| SCHEMBL7117253 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2TDP1MAPTKDM4ETHRB | |
| SCHEMBL7117245 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2TDP1MAPTKDM4ETHRB | |
| SCHEMBL14930732 | 0.79 | L3MBTL1 (0.46) | SMN1; SMN2TDP1PLA2G2CMAPTKDM4E | |
| SCHEMBL8628765 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1PLA2G2CMAPTKDM4E | |
| SCHEMBL2791101 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1PLA2G2CMAPTKDM4E | |
| SCHEMBL2791099 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1PLA2G2CMAPTKDM4E | |
| SCHEMBL11234232 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2TDP1MAPTKDM4ETHRB | |
| SCHEMBL11234237 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2TDP1MAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6808716-B2 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2004-10-26 | — | — | US | claimed |
| WO-2004089329-A2 | TOPICAL COMPOSITIONS COMPRISING N-ACETYLAMINO ACIDS OR RELATED N-ACETYL COMPOUNDS | YU RUEY J (US) | 2004-10-21 | — | — | WO | claimed |
| US-20030198656-A1 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2003-10-23 | — | — | US | claimed |
| US-6808716-B2 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2004-10-26 | — | — | US | disclosed |
| US-20030229141-A1 | N-acetyl cysteine and its topical use | YU RUEY J (US) | 2003-12-11 | — | — | US | disclosed |
| US-20030198656-A1 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2003-10-23 | — | — | US | disclosed |