SCHEMBL7119633

SCHEMBL7119633

CCOC(=O)N1CC=C(c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2)C1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.48
F10 P00742 8/20 0.47
MAOB P27338 2/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
CALML3 P27482 1/20 0.47
SDHA P31040 1/20 0.47
ITGB3 P05106 3/20 0.45
PRSS1 P07477 3/20 0.45
PRSS2 P07478 3/20 0.45
ITGA2B P08514 3/20 0.45
PRSS3 P35030 3/20 0.45
F2 P00734 1/20 0.44
CMA1 P23946 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7123626 0.90 F10 (0.46) MAOAF10MAOBLMNAPTGS1
SCHEMBL6402405 0.84 MAOA (0.49) MAOAF10MAOBLMNAPTGS1
SCHEMBL6402400 0.84 MAOA (0.49) MAOAF10MAOBLMNAPTGS1
SCHEMBL8139877 0.84 MAOA (0.46) MAOAF10MAOBLMNAPTGS1
SCHEMBL6401956 0.84 F10 (0.45) MAOAF10MAOBLMNAPTGS1
SCHEMBL6401959 0.84 F10 (0.45) MAOAF10MAOBLMNAPTGS1
SCHEMBL7128269 0.83 MAOA (0.42) MAOAF10MAOBLMNAPTGS1
SCHEMBL7126743 0.83 MAOA (0.52) MAOAF10MAOBLMNAPTGS1
SCHEMBL7126969 0.82 MAOA (0.50) MAOAF10MAOBLMNAPTGS1
SCHEMBL6397247 0.81 MAOA (0.48) MAOAF10MAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216374-A1 Antibiotic oxazolidinone derivatives SYNGENTA LIMITED (GB) 2003-11-20 US disclosed
US-6605630-B1 Active against drug resistant gram positive pathogens SYNGENTA LIMITED (GB) 2003-08-12 US disclosed
EP-1005468-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 2000-06-07 EP disclosed
WO-1999010342-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1999-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216374-A1 Antibiotic oxazolidinone derivatives OXA1L, HRH1, OGDH MAOA 1078/4885F10 795/4885MAOB 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.