SCHEMBL7123626

SCHEMBL7123626

CC(=O)NC[C@H]1CN(c2ccc(C3=CCN(C(=O)OCc4ccccc4)C3)cc2)C(=O)O1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.46
MAOA P21397 5/20 0.45
MAOB P27338 2/20 0.43
LMNA P02545 1/20 0.43
PTGS1 P23219 1/20 0.43
CALML3 P27482 1/20 0.43
SDHA P31040 1/20 0.43
ABCB11 O95342 1/20 0.41
GRM2 Q14416 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6401959 0.93 F10 (0.45) F10MAOAMAOBLMNAPTGS1
SCHEMBL6401956 0.93 F10 (0.45) F10MAOAMAOBLMNAPTGS1
SCHEMBL7119633 0.90 MAOA (0.48) F10MAOAMAOBLMNAPTGS1
SCHEMBL8139877 0.85 MAOA (0.46) F10MAOAMAOBLMNAPTGS1
SCHEMBL7821646 0.84 MAOA (0.48) F10MAOAMAOBLMNAPTGS1
SCHEMBL8135586 0.82 F10 (0.41) F10MAOAMAOBLMNAPTGS1
SCHEMBL6292471 0.82 TMEM97 (0.60) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL10151525 0.81 MAOA (0.51) F10MAOAMAOBLMNAPTGS1
SCHEMBL7128269 0.81 MAOA (0.42) F10MAOAMAOBLMNAPTGS1
SCHEMBL7129096 0.81 F10 (0.41) F10MAOAMAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216374-A1 Antibiotic oxazolidinone derivatives SYNGENTA LIMITED (GB) 2003-11-20 US disclosed
US-6605630-B1 Active against drug resistant gram positive pathogens SYNGENTA LIMITED (GB) 2003-08-12 US disclosed
EP-1005468-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 2000-06-07 EP disclosed
WO-1999010342-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1999-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216374-A1 Antibiotic oxazolidinone derivatives OXA1L, HRH1, OGDH F10 795/4885MAOA 1078/4885MAOB 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.