Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417306 | 0.88 | TSHR (0.68) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL264625 | 0.86 | ERN1 (0.54) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL29106822 | 0.86 | GABRA1 (0.56) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL13331594 | 0.83 | ERN1 (0.52) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL9148389 | 0.82 | ERN1 (0.50) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL9051365 | 0.82 | ERN1 (0.50) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL1163160 | 0.82 | ERN1 (0.50) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL14151513 | 0.82 | ERN1 (0.50) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL3355916 | 0.82 | ERN1 (0.50) | ERN1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL582239 | 0.80 | TSHR (0.68) | ERN1TSHRCYP3A4TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693032-B | A kind of bio-pharmaceuticals factory organic wastewater treating system and its processing method | 江苏建筑职业技术学院 | 2018-05-25 | — | — | CN | claimed |
| CN-106124646-A | A kind of detect the method for polarity phenol chloro/bromo disinfection byproduct (DBP) in water | 南京大学 | 2016-11-16 | — | — | CN | claimed |
| CN-105693032-A | Biological pharmaceutical factory organic wastewater treatment system and treatment method | 江苏建筑职业技术学院 | 2016-06-22 | — | — | CN | claimed |
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | claimed |
| JP-59013793-A | — | — | None | — | — | JP | disclosed |
| CN-117886760-A | Synthesis method of 3- (5-fluoropyrimidine-2-yl) -2-methoxy aniline | 爱斯特（成都）生物制药股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-11440989-B2 | Application of Mannich base in flame-retardant polyurethane material | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2022-09-13 | — | — | US | disclosed |
| US-11401375-B2 | Flame-retardant polyether polyol as well as preparation method and application thereof | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2022-08-02 | — | — | US | disclosed |
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |
| US-20200283562-A1 | APPLICATION OF MANNICH BASE IN FLAME-RETARDANT POLYURETHANE MATERIAL | JIAHUA CHEMICALS INC. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-20200283573-A1 | FLAME-RETARDANT POLYETHER POLYOL AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-10722514-B2 | Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof | RAPT THERAPEUTICS, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-4913821-A | Method for the determination of phenols in water | THE DOW CHEMICAL COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4822804-A | 5,6,7,-trinor-4,8-inter-m-phenylene 2-nor PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4564620-A | 5,6,7,-Trinor-4,8-inter-m-phenylene PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0060640-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1985-11-13 | — | — | EP | disclosed |
| JP-S5913793-A | ORGANIC PHOSPHORIC ESTER COMPOUND, ITS PREPARATION, INSECTICIDE AND ACARICIDE CONTAINING IT AS ACTIVE INGREDIENT | KANESHO KK | 1984-01-24 | — | — | JP | disclosed |
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |
| US-4313977-A | FORMING WATER INSOLUBLE ORGANIC SALT OF PHENOL | THE DOW CHEMICAL COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4010252-A | POLYQUATERNARY AMMONIUM COMPOUND, DEODORANTS | COLGATE-PALMOLIVE COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440989-B2 | Application of Mannich base in flame-retardant polyurethane material | FBL, HNRNPUL2, HNRNPUL1 | ERN1 660/4885TSHR 2890/4885CYP3A4 2597/4885 |
| US-10722514-B2 | Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof | USP7, SENP7, USP8 | ERN1 459/4885TSHR 3825/4885CYP3A4 3186/4885 |
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | ERN1 459/4885TSHR 3825/4885CYP3A4 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.