Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6566761 | 0.90 | GAA (0.38) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL526857 | 0.89 | ALDH1A1 (0.48) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL3336490 | 0.88 | ALDH1A1 (0.47) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9820908 | 0.88 | ALDH1A1 (0.47) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL30338656 | 0.88 | ALDH1A1 (0.47) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL11417011 | 0.87 | ALDH1A1 (0.45) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7079849 | 0.86 | ALDH1A1 (0.45) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL8444717 | 0.85 | GAA (0.46) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Water SCHEMBL7079816 | 0.84 | ALDH1A1 (0.44) | GAAL3MBTL1MAPTALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL5699530 | 0.84 | GAA (0.37) | GAAL3MBTL1MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6551767-B1 | Forming a free-base and water mixture; heating free-base and water mixture to effect formation of a free-base layer and a water layer; separating liquid free-base layer from said water layer; mixing with water soluble solvent | EASTMAN CHEMICAL COMPANY | 2003-04-22 | — | — | US | disclosed |